the good doctor on: What is all the hub-bub about omega 3’s?

Blog Vol.II, # 5. What is all the hub-bub about omega 3’s?

There has been a lot of discussion about the benefits of taking omega 3 fatty acids. Initially, increased omega 3 was linked to a reduction of triglyceride levels in the blood and thus linked to a reduction in the risk of cardiovascular disease. More recently, omega 3 has been found helpful in the reduction of inflammation and eye dryness. A few blogs ago I discussed Tarsal glands and their critical role in stable, healthy tear formation and overall eye health. Omega 3’s are the oils that end up in these glands and enhance their functioning.

Recommended daily doses of omega 3 are in the 3000 mg range for a combination of DHA (Docosahexaenoic acid) and EPA (Eicosapentaenoic acid), two different types of omega 3. To get that much omega 3 one would have to consume 37 tins of tuna every week. There are so many reasons why that’s not going to happen. I don’t even think Hobbes, Calvin’s feline friend, would go through that much tuna in a week.

To make the consumption of the recommended omega 3 possible, the fish oils have been concentrated into a liquid or soft gel form for daily consumption. The problem is that these new esterified forms are nasty tasting and not readily absorbed by the body. It takes another step to make these concentrated oils reform back to the triglyceride form, which is the best form for our purposes.

At Burlington Eyecare we use PRN brand omega 3’s for treating dry eye. There are other brands out there, such as Nutrasea, that also provide the most useable omega 3. The body breaks down the fatty acid chains into their constituent parts and they arrive at the Tarsal glands to make the free flowing meibum that we all need to prevent dry eyes. Not all omega 3’s on the market, however, have been returned to the triglyceride form, so the consumer is not getting the full benefit of the omega 3’s they are consuming. Do your research.

Omega 3’s do have some side effects, like causing some blood thinning, so if you are already on a blood thinner, consult your physician. Omega 3’s can also reduce your blood pressure, again a word of caution if you are already on anti-hypertensives.

Wanted side-effects, are the reduction of inflammation throughout the body, for instance in helping with rheumatoid arthritis and reduced risk in heart disease.

We prescribe Omega 3 fatty acids for Dry Eye Disease, and for specific conditions like Acne Rosacea. Once again, we recommend an eye exam and, if necessary, a dry eye assessment.

Til next week,

the good doctor, Dr. Mark Germain, Burlington Optometrist


The good doctor take a deeper look at how gut health is connected to eye tissues.
By Dr. Mark Germain April 29, 2026
Blog vol 6.40. The Gut and the Eyes. One of my biggest jobs is to keep abreast of new research and advances in eye health. Most recently, we have seen new stem cell research, gene therapies, as well as new drugs for dry and wet macular degeneration. In January of this year, there was an article in the journal, Cell Death and Disease, that looked at cell apoptosis, specifically with the photoreceptors of the eye. (Read the article here ). Apoptosis is the genetic programming of deliberate and constructive cell death, allowing for the maintenance of healthy structures and systems in the body. Some estimates have the body replacing 50 to 70 billion cells daily by this process. Necrosis, on the other hand, is unplanned cell death caused by injury, toxins, or other negative outside factors; this causes inflammation and disrupts the body’s balance of things. There are stressors that speed up cell turnover. The study looked at photoreceptors in the retina and were able to demonstrate cellular recovery, even in late stages of apoptosis, recovery not breakdown. When certain stressors were reduced, by working with the mitochondria, there was recovery of the photoreceptor cells. How? Mitophagy, the mitochondria’s own process of programmed breaking down and then repurposing the recycled components for new ones. This mitochondrial repair helps to reverse the sequence of apoptosis for the photoreceptors. Mitochondria, how cool. How is this helpful for our eyes? Conditions like retinitis pigmentosa or macular degeneration directly involve the photoreceptors and may be slowed or reversed by helping the mitochondria. So, let’s take care of those mitochondria. There is some evidence for nutritional support for the mitochondrial system. The nutrient, Urolithin A (UA), which is a compound made in our gut from fiber found in pomegranates, berries, and nuts is the only clinically proven substance known to trigger mitophagy, made in the gut no less. Vitamin B3 is critical for mitochondria function, however vitamin B3 based supplements are still to be clinically tested for their support of cell recovery. Nutrients Coenzyme Q10 and L-carnitine are known to help the mitochondria generate energy, and interestingly, infrared light therapy has also been shown to benefit mitochondrial function. Again, food for thought. The gut and its function needs a lot of research. How do probiotics and nutrient precursors affect eye tissues? It is so interesting that the gut can be a factor in eye health. Maybe adding Urolithin A as a supplement is wise, along with the antioxidants in Lutein and Zeaxanthin we use to combat photoreceptor degeneration. Will keep you posted on any new developments.  The good doctor
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